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Late‐Stage Modification of Aminoglycoside Antibiotics Overcomes Bacterial Resistance Mediated by APH(3’) Kinases
The continuous emergence of antimicrobial resistance is causing a threat to patients infected by multidrug‐resistant pathogens. In particular, the clinical use of aminoglycoside antibiotics, broad‐spectrum antibacterials of last resort, is limited due to rising bacterial resistance. One of the major...
Autores principales: | Bastian, Andreas A., Bastian, Maria, Jäger, Manuel, Loznik, Mark, Warszawik, Eliza M., Yang, Xintong, Tahiri, Nabil, Fodran, Peter, Witte, Martin D., Thoma, Anne, Köhler, Jens, Minnaard, Adriaan J., Herrmann, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321007/ https://www.ncbi.nlm.nih.gov/pubmed/35388562 http://dx.doi.org/10.1002/chem.202200883 |
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