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Late‐Stage Modification of Aminoglycoside Antibiotics Overcomes Bacterial Resistance Mediated by APH(3’) Kinases

The continuous emergence of antimicrobial resistance is causing a threat to patients infected by multidrug‐resistant pathogens. In particular, the clinical use of aminoglycoside antibiotics, broad‐spectrum antibacterials of last resort, is limited due to rising bacterial resistance. One of the major...

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Detalles Bibliográficos
Autores principales: Bastian, Andreas A., Bastian, Maria, Jäger, Manuel, Loznik, Mark, Warszawik, Eliza M., Yang, Xintong, Tahiri, Nabil, Fodran, Peter, Witte, Martin D., Thoma, Anne, Köhler, Jens, Minnaard, Adriaan J., Herrmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321007/
https://www.ncbi.nlm.nih.gov/pubmed/35388562
http://dx.doi.org/10.1002/chem.202200883

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