Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes

A Ni‐catalyzed C(sp2)−OMe ortho‐functionalization methodology to form chemoselectively alkyne monoannulation or aromatic homologation products is reported as a novel protocol towards the valorisation of substrates containing C(sp2)−OMe units. Double activation of C(sp2)−OMe and C(sp2)−F bonds is als...

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Autores principales: Capdevila, Lorena, Sala, Judith, Ackermann, Lutz, Ribas, Xavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321019/
https://www.ncbi.nlm.nih.gov/pubmed/35322915
http://dx.doi.org/10.1002/chem.202200625
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author Capdevila, Lorena
Sala, Judith
Ackermann, Lutz
Ribas, Xavi
author_facet Capdevila, Lorena
Sala, Judith
Ackermann, Lutz
Ribas, Xavi
author_sort Capdevila, Lorena
collection PubMed
description A Ni‐catalyzed C(sp2)−OMe ortho‐functionalization methodology to form chemoselectively alkyne monoannulation or aromatic homologation products is reported as a novel protocol towards the valorisation of substrates containing C(sp2)−OMe units. Double activation of C(sp2)−OMe and C(sp2)−F bonds is also demonstrated. Further use of aromatic homologation products towards the synthesis of nanographene‐like compounds is described.
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spelling pubmed-93210192022-07-30 Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes Capdevila, Lorena Sala, Judith Ackermann, Lutz Ribas, Xavi Chemistry Research Articles A Ni‐catalyzed C(sp2)−OMe ortho‐functionalization methodology to form chemoselectively alkyne monoannulation or aromatic homologation products is reported as a novel protocol towards the valorisation of substrates containing C(sp2)−OMe units. Double activation of C(sp2)−OMe and C(sp2)−F bonds is also demonstrated. Further use of aromatic homologation products towards the synthesis of nanographene‐like compounds is described. John Wiley and Sons Inc. 2022-04-07 2022-05-19 /pmc/articles/PMC9321019/ /pubmed/35322915 http://dx.doi.org/10.1002/chem.202200625 Text en © 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Capdevila, Lorena
Sala, Judith
Ackermann, Lutz
Ribas, Xavi
Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title_full Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title_fullStr Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title_full_unstemmed Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title_short Nickel‐Catalyzed C(sp2)−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes
title_sort nickel‐catalyzed c(sp2)−ome functionalization for chemoselective aromatic homologation en route to nanographenes
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321019/
https://www.ncbi.nlm.nih.gov/pubmed/35322915
http://dx.doi.org/10.1002/chem.202200625
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