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ZLM-7 Blocks Breast Cancer Progression by Inhibiting MDM2 via Upregulation of 14-3-3 Sigma

Breast cancer is one of the most prevalent malignancies with poor prognosis. Inhibition of angiogenesis is becoming a valid and evident therapeutic strategy to treat cancer. Recent studies uncovered the antiangiogenic activity of ZLM-7 (a combretastain A-4 derivative), but the regulatory mechanism i...

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Detalles Bibliográficos
Autores principales: Wen, Min, Zou, Zi-Zheng, Luo, Tiao, Li, Xuan, Liu, Su-You, Li, Ji-Jia, Luo, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321038/
https://www.ncbi.nlm.nih.gov/pubmed/35890172
http://dx.doi.org/10.3390/ph15070874