Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group

The aggressive nature of the activated B cell such as (ABC) subtype of diffuse large B cell (DLBCL) is frequently associated with altered B cell Receptor (BCR) signaling through the activation of key components including the scaffolding protein, CARD11. Most inhibitors, such as ibrutinib, target dow...

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Detalles Bibliográficos
Autores principales: Swafford, Kennith, Acharya, Baku, Xu, Ying-Zhi, Raney, Thomas, McCrury, Mason, Saha, Debasmita, Frett, Brendan, Kendrick, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321325/
https://www.ncbi.nlm.nih.gov/pubmed/35885931
http://dx.doi.org/10.3390/genes13071144

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