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Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District

People Living with HIV (PLHIV) are often dealing with a range of issues that make life more difficult because of the limited emotional, spiritual, psychological, social, physical and clinical support which consequently lead to poor physical health and quality of life. The holistic care of individual...

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Autores principales: Sendaula, Emmanuel, Buwembo, Michael, Opio, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321371/
https://www.ncbi.nlm.nih.gov/pubmed/35881616
http://dx.doi.org/10.1371/journal.pone.0272039
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author Sendaula, Emmanuel
Buwembo, Michael
Opio, Denis
author_facet Sendaula, Emmanuel
Buwembo, Michael
Opio, Denis
author_sort Sendaula, Emmanuel
collection PubMed
description People Living with HIV (PLHIV) are often dealing with a range of issues that make life more difficult because of the limited emotional, spiritual, psychological, social, physical and clinical support which consequently lead to poor physical health and quality of life. The holistic care of individuals infected with HIV/AIDS involves promoting psychological and physiological well-being as well as fostering socio-cultural relationships and supporting the fulfillment of spiritual aspirations. We conducted a retrospective cross-sectional study among HIV-infected patients receiving a holistic approach of care model from January 2015 to December 2018 in Kampala district, Uganda. The study involved adult individuals aged 18 and above from whom demographics and other information were obtained. All eligible participants were selected using stratified random sampling from the parishes and systematic random sampling to select study participants. We investigated the clinical profile and the factors associated with viral load suppression among HIV-infected patients receiving a holistic approach of care model in Kampala District. The data was analyzed using STATA version 13. 0. Results: A total of 910 patients were enrolled. 676 (74.3%) were female; 453 (49.8%) were between 18 and 39 years. 324 (35.6%) were either overweight or obese. 769 (84.5%) had viral load beyond detectable limits, 904 (99.3%) were adhering to HIV treatment. 867(95.3%) were virally suppressed. The age group 40–59 years (Adjusted Odds Ratio (aOR) = 2.85, 95% Confidence Interval (CI):1.36–5.97, P = 0.005) and good adherence (aOR = 12.9, 95%CI:1.86–81.07, P = 0.009) were significantly associated with viral load suppression. Conclusion: The holistic care model supports patients in all facets of their lives, resulting into improved treatment outcomes. Our findings show that age and adherence are linked to viral load suppression among HIV-infected adults receiving a holistic approach of care model.
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spelling pubmed-93213712022-07-27 Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District Sendaula, Emmanuel Buwembo, Michael Opio, Denis PLoS One Research Article People Living with HIV (PLHIV) are often dealing with a range of issues that make life more difficult because of the limited emotional, spiritual, psychological, social, physical and clinical support which consequently lead to poor physical health and quality of life. The holistic care of individuals infected with HIV/AIDS involves promoting psychological and physiological well-being as well as fostering socio-cultural relationships and supporting the fulfillment of spiritual aspirations. We conducted a retrospective cross-sectional study among HIV-infected patients receiving a holistic approach of care model from January 2015 to December 2018 in Kampala district, Uganda. The study involved adult individuals aged 18 and above from whom demographics and other information were obtained. All eligible participants were selected using stratified random sampling from the parishes and systematic random sampling to select study participants. We investigated the clinical profile and the factors associated with viral load suppression among HIV-infected patients receiving a holistic approach of care model in Kampala District. The data was analyzed using STATA version 13. 0. Results: A total of 910 patients were enrolled. 676 (74.3%) were female; 453 (49.8%) were between 18 and 39 years. 324 (35.6%) were either overweight or obese. 769 (84.5%) had viral load beyond detectable limits, 904 (99.3%) were adhering to HIV treatment. 867(95.3%) were virally suppressed. The age group 40–59 years (Adjusted Odds Ratio (aOR) = 2.85, 95% Confidence Interval (CI):1.36–5.97, P = 0.005) and good adherence (aOR = 12.9, 95%CI:1.86–81.07, P = 0.009) were significantly associated with viral load suppression. Conclusion: The holistic care model supports patients in all facets of their lives, resulting into improved treatment outcomes. Our findings show that age and adherence are linked to viral load suppression among HIV-infected adults receiving a holistic approach of care model. Public Library of Science 2022-07-26 /pmc/articles/PMC9321371/ /pubmed/35881616 http://dx.doi.org/10.1371/journal.pone.0272039 Text en © 2022 Sendaula et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sendaula, Emmanuel
Buwembo, Michael
Opio, Denis
Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title_full Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title_fullStr Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title_full_unstemmed Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title_short Clinical profile of HIV-infected adults receiving a holistic approach of care model in Nakawa, Kampala District
title_sort clinical profile of hiv-infected adults receiving a holistic approach of care model in nakawa, kampala district
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321371/
https://www.ncbi.nlm.nih.gov/pubmed/35881616
http://dx.doi.org/10.1371/journal.pone.0272039
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