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TNFα-induced metabolic reprogramming drives an intrinsic anti-viral state
Cytokines induce an anti-viral state, yet many of the functional determinants responsible for limiting viral infection are poorly understood. Here, we find that TNFα induces significant metabolic remodeling that is critical for its anti-viral activity. Our data demonstrate that TNFα activates glycol...
Autores principales: | Ciesla, Jessica, Moreno, Isreal, Munger, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321404/ https://www.ncbi.nlm.nih.gov/pubmed/35834576 http://dx.doi.org/10.1371/journal.ppat.1010722 |
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