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TNFα-induced metabolic reprogramming drives an intrinsic anti-viral state

Cytokines induce an anti-viral state, yet many of the functional determinants responsible for limiting viral infection are poorly understood. Here, we find that TNFα induces significant metabolic remodeling that is critical for its anti-viral activity. Our data demonstrate that TNFα activates glycol...

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Detalles Bibliográficos
Autores principales: Ciesla, Jessica, Moreno, Isreal, Munger, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321404/
https://www.ncbi.nlm.nih.gov/pubmed/35834576
http://dx.doi.org/10.1371/journal.ppat.1010722

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