Cargando…
A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function
BACKGROUND: Neutrophil activation drives lung complications after cardiopulmonary bypass (CPB). Evidence suggests the healthy, ventilated lung may beneficially re-condition pro-inflammatory neutrophils. However, evidence in humans is lacking, due to a paucity of good models. CPB with simultaneous ce...
Autores principales: | Funston, Wendy, Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Powell, Jason, Cooles, Faye A. H., Shelmerdine, Lauren, McDowell, Cliona, O’Leary, Denis, Booth, Karen L., Clark, Stephen C., Ledingham, Simon J., Rostron, Anthony J., Dark, John H., Simpson, A. John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321419/ https://www.ncbi.nlm.nih.gov/pubmed/35881612 http://dx.doi.org/10.1371/journal.pone.0271958 |
Ejemplares similares
-
Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury
por: Macfarlane, James G., et al.
Publicado: (2020) -
Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ
por: Widdrington, John D., et al.
Publicado: (2017) -
Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses
por: Widdrington, John D., et al.
Publicado: (2018) -
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function
por: Ruchaud-Sparagano, Marie-Hélène, et al.
Publicado: (2007) -
Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli
por: Mühlen, Sabrina, et al.
Publicado: (2011)