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Species specific morphological alterations in liver tissue after biliary occlusion in rat and mouse: Similar but different

BACKGROUND: The selection of the appropriate species is one of the key issues in experimental medicine. Bile duct ligation is the mostly used experimental model in rodents to explore special aspects of occlusive cholestasis. We aimed to clarify if rats or mice are suitable for the same or different...

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Detalles Bibliográficos
Autores principales: Richter, Beate, Sänger, Constanze, Mussbach, Franziska, Scheuerlein, Hubert, Settmacher, Utz, Dahmen, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321426/
https://www.ncbi.nlm.nih.gov/pubmed/35881613
http://dx.doi.org/10.1371/journal.pone.0271975