Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2

Granzyme K (GzmK) is a tryptic member of the granzyme family of chymotrypsin-like serine proteases produced by cells of the immune system. Previous studies have indicated that GzmK activates protease-activated receptor 1 (PAR1) enhancing activation of monocytes and wound healing in endothelial cells...

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Detalles Bibliográficos
Autores principales: Kaiserman, Dion, Zhao, Peishen, Rowe, Caitlin Lorraine, Leong, Andrea, Barlow, Nicholas, Joeckel, Lars Thomas, Hitchen, Corinne, Stewart, Sarah Elizabeth, Hollenberg, Morley D., Bunnett, Nigel, Suhrbier, Andreas, Bird, Phillip Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321427/
https://www.ncbi.nlm.nih.gov/pubmed/35881628
http://dx.doi.org/10.1371/journal.pone.0270584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321427/
https://www.ncbi.nlm.nih.gov/pubmed/35881628
http://dx.doi.org/10.1371/journal.pone.0270584

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