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Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2
Granzyme K (GzmK) is a tryptic member of the granzyme family of chymotrypsin-like serine proteases produced by cells of the immune system. Previous studies have indicated that GzmK activates protease-activated receptor 1 (PAR1) enhancing activation of monocytes and wound healing in endothelial cells...
Autores principales: | Kaiserman, Dion, Zhao, Peishen, Rowe, Caitlin Lorraine, Leong, Andrea, Barlow, Nicholas, Joeckel, Lars Thomas, Hitchen, Corinne, Stewart, Sarah Elizabeth, Hollenberg, Morley D., Bunnett, Nigel, Suhrbier, Andreas, Bird, Phillip Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321427/ https://www.ncbi.nlm.nih.gov/pubmed/35881628 http://dx.doi.org/10.1371/journal.pone.0270584 |
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