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First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017

BACKGROUND: Dengue’s emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation’s largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were centered. METHODOLOGY: In 12...

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Autores principales: Badolo, Athanase, Sombié, Aboubacar, Yaméogo, Félix, Wangrawa, Dimitri W., Sanon, Aboubakar, Pignatelli, Patricia M., Sanon, Antoine, Viana, Mafalda, Kanuka, Hirotaka, Weetman, David, McCall, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321428/
https://www.ncbi.nlm.nih.gov/pubmed/35793379
http://dx.doi.org/10.1371/journal.pntd.0010059
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author Badolo, Athanase
Sombié, Aboubacar
Yaméogo, Félix
Wangrawa, Dimitri W.
Sanon, Aboubakar
Pignatelli, Patricia M.
Sanon, Antoine
Viana, Mafalda
Kanuka, Hirotaka
Weetman, David
McCall, Philip J.
author_facet Badolo, Athanase
Sombié, Aboubacar
Yaméogo, Félix
Wangrawa, Dimitri W.
Sanon, Aboubakar
Pignatelli, Patricia M.
Sanon, Antoine
Viana, Mafalda
Kanuka, Hirotaka
Weetman, David
McCall, Philip J.
author_sort Badolo, Athanase
collection PubMed
description BACKGROUND: Dengue’s emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation’s largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were centered. METHODOLOGY: In 1200LG (urban), Tabtenga (peri-urban) and Goundry (rural) localities, we collected indoor and outdoor resting mosquito adults, characterized larval habitats and containers producing pupae and reared immature stages to adulthood in the laboratory for identification. All mosquito adults were identified morphologically. Host species (from which bloodmeals were taken) were identified by PCR. Generalized mixed models were used to investigate relationships between adult or larval densities and multiple explanatory variables. RESULTS: From samples in 1,780 houses, adult Ae. aegypti were significantly more abundant in the two urban localities (Tabtenga and 1200 LG) in both years than in the rural site (Goundry), where Anopheles spp. were far more common. Results from adult collections indicated a highly exophilic and anthropophilic (>90% bloodmeals of human origin) vector population, but with a relatively high proportion of bloodfed females caught inside houses. Habitats producing most pupae were waste tires (37% of total pupae), animal troughs (44%) and large water barrels (30%). While Stegomyia indices were not reliable indicators of adult mosquito abundance, shared influences on adult and immature stage densities included rainfall and container water level, collection month and container type/purpose. Spatial analysis showed autocorrelation of densities, with a partial overlap in adult and immature stage hotspots. CONCLUSION: Results provide an evidence base for the selection of appropriate vector control methods to minimize the risk, frequency and magnitude of future outbreaks in Ouagadougou. An integrated strategy combining community-driven practices, waste disposal and insecticide-based interventions is proposed. The prospects for developing a regional approach to arbovirus control in West Africa or across Africa are discussed.
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spelling pubmed-93214282022-07-27 First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017 Badolo, Athanase Sombié, Aboubacar Yaméogo, Félix Wangrawa, Dimitri W. Sanon, Aboubakar Pignatelli, Patricia M. Sanon, Antoine Viana, Mafalda Kanuka, Hirotaka Weetman, David McCall, Philip J. PLoS Negl Trop Dis Research Article BACKGROUND: Dengue’s emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation’s largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were centered. METHODOLOGY: In 1200LG (urban), Tabtenga (peri-urban) and Goundry (rural) localities, we collected indoor and outdoor resting mosquito adults, characterized larval habitats and containers producing pupae and reared immature stages to adulthood in the laboratory for identification. All mosquito adults were identified morphologically. Host species (from which bloodmeals were taken) were identified by PCR. Generalized mixed models were used to investigate relationships between adult or larval densities and multiple explanatory variables. RESULTS: From samples in 1,780 houses, adult Ae. aegypti were significantly more abundant in the two urban localities (Tabtenga and 1200 LG) in both years than in the rural site (Goundry), where Anopheles spp. were far more common. Results from adult collections indicated a highly exophilic and anthropophilic (>90% bloodmeals of human origin) vector population, but with a relatively high proportion of bloodfed females caught inside houses. Habitats producing most pupae were waste tires (37% of total pupae), animal troughs (44%) and large water barrels (30%). While Stegomyia indices were not reliable indicators of adult mosquito abundance, shared influences on adult and immature stage densities included rainfall and container water level, collection month and container type/purpose. Spatial analysis showed autocorrelation of densities, with a partial overlap in adult and immature stage hotspots. CONCLUSION: Results provide an evidence base for the selection of appropriate vector control methods to minimize the risk, frequency and magnitude of future outbreaks in Ouagadougou. An integrated strategy combining community-driven practices, waste disposal and insecticide-based interventions is proposed. The prospects for developing a regional approach to arbovirus control in West Africa or across Africa are discussed. Public Library of Science 2022-07-06 /pmc/articles/PMC9321428/ /pubmed/35793379 http://dx.doi.org/10.1371/journal.pntd.0010059 Text en © 2022 Badolo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Badolo, Athanase
Sombié, Aboubacar
Yaméogo, Félix
Wangrawa, Dimitri W.
Sanon, Aboubakar
Pignatelli, Patricia M.
Sanon, Antoine
Viana, Mafalda
Kanuka, Hirotaka
Weetman, David
McCall, Philip J.
First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title_full First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title_fullStr First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title_full_unstemmed First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title_short First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017
title_sort first comprehensive analysis of aedes aegypti bionomics during an arbovirus outbreak in west africa: dengue in ouagadougou, burkina faso, 2016–2017
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321428/
https://www.ncbi.nlm.nih.gov/pubmed/35793379
http://dx.doi.org/10.1371/journal.pntd.0010059
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