Cargando…

Non-invasive skin sampling detects systemically administered drugs in humans

Clinical testing typically relies on invasive blood draws and biopsies. Alternative methods of sample collection are continually being developed to improve patient experience; swabbing the skin is one of the least invasive sampling methods possible. To show that skin swabs in combination with untarg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Panitchpakdi, Morgan, Weldon, Kelly C., Jarmusch, Alan K., Gentry, Emily C., Choi, Arianna, Sepulveda, Yadira, Aguirre, Shaden, Sun, Kunyang, Momper, Jeremiah D., Dorrestein, Pieter C., Tsunoda, Shirley M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321436/ https://www.ncbi.nlm.nih.gov/pubmed/35881585 http://dx.doi.org/10.1371/journal.pone.0271794

Ejemplares similares

Physicochemical properties determining drug detection in skin
por: Bittremieux, Wout, et al.
Publicado: (2021)

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study
por: Jarmusch, Alan K., et al.
Publicado: (2020)

Multifactor Quality and Safety Analysis of Antimicrobial Drugs Sold by Online Pharmacies That Do Not Require a Prescription: Multiphase Observational, Content Analysis, and Product Evaluation Study
por: Mackey, Tim Ken, et al.
Publicado: (2022)

Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability
por: Tsunoda, Shirley M., et al.
Publicado: (2021)

Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity
por: Fang, Xin, et al.
Publicado: (2020)

The Molecular Effect of Wearing Silver-Threaded Clothing on the Human Skin
por: Melnik, Alexey V., et al.
Publicado: (2023)

Fine scale transitions of the microbiota and metabolome along the gastrointestinal tract of herbivorous fishes
por: Sparagon, Wesley J., et al.
Publicado: (2022)

Microbiomes and metabolomes of dominant coral reef primary producers illustrate a potential role for immunolipids in marine symbioses
por: Mannochio-Russo, Helena, et al.
Publicado: (2023)

An untargeted metabolomics analysis of exogenous chemicals in human milk and transfer to the infant
por: Thomas, Sydney, et al.
Publicado: (2022)

Publisher Correction: Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery
por: Behsaz, Bahar, et al.
Publicado: (2021)

Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery
por: Behsaz, Bahar, et al.
Publicado: (2021)

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides
por: Aleti, Gajender, et al.
Publicado: (2022)

The impact of skin care products on skin chemistry and microbiome dynamics
por: Bouslimani, Amina, et al.
Publicado: (2019)

Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic
por: Vrbanac, Alison, et al.
Publicado: (2020)

The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases
por: Fogelson, Kelly A., et al.
Publicado: (2023)

Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae)
por: Martin H., Christian, et al.
Publicado: (2020)

High-confidence structural annotation of metabolites absent from spectral libraries
por: Hoffmann, Martin A., et al.
Publicado: (2021)

A sample implementation for parallelizing Divide-and-Conquer algorithms on the GPU
por: Mei, Gang, et al.
Publicado: (2018)

Depression in Individuals Coinfected with HIV and HCV Is Associated with Systematic Differences in the Gut Microbiome and Metabolome
por: Taylor, Bryn C., et al.
Publicado: (2020)

Ion identity molecular networking for mass spectrometry-based metabolomics in the GNPS environment
por: Schmid, Robin, et al.
Publicado: (2021)

Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme
por: Dulchavsky, Mark, et al.
Publicado: (2023)

Metabolome-Informed Microbiome Analysis Refines Metadata Classifications and Reveals Unexpected Medication Transfer in Captive Cheetahs
por: Gauglitz, Julia M., et al.
Publicado: (2020)

2551. Assessing Meropenem Concentrations in Children with Septic Shock: Population-Based Pharmacokinetic (PK) Modeling of Meropenem Demonstrates Variability from Acute Kidney (AKI) to Augmented Renal Clearance (ARC)
por: Le, Jennifer, et al.
Publicado: (2023)

How to Administer Quinine
por: MacGilchrist, A. C.
Publicado: (1917)

Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats
por: Youn, Nam Hee, et al.
Publicado: (2020)

The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology
por: Nigam, Sanjay K., et al.
Publicado: (2020)

From Sample to Multi-Omics Conclusions in under 48 Hours
por: Quinn, Robert A., et al.
Publicado: (2016)

Molecular inter-kingdom interactions of endophytes isolated from Lychnophora ericoides
por: Caraballo-Rodríguez, Andrés M., et al.
Publicado: (2017)

El sistema administrador de mercaderías para el grupo Chedraui
por: Aguirre Reyes, Yadira
Publicado: (1999)

Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection
por: Mu, Andre, et al.
Publicado: (2021)

Estimation of Kidney Function in Patients With Multiple Myeloma: Implications for Lenalidomide Dosing
por: Salama, Engie, et al.
Publicado: (2022)

Deploying and administering Windows Vista Bible
por: Kelly, Bob, et al.
Publicado: (2008)

Targeted Capture and Heterologous Expression of the Pseudoalteromonas Alterochromide Gene Cluster in Escherichia coli Represents a Promising Natural Product Exploratory Platform
por: Ross, Avena C., et al.
Publicado: (2014)

Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis
por: O'Hayre, Morgan, et al.
Publicado: (2010)

Reliability of Internet- Versus Telephone-Administered Questionnaires in a Diverse Sample of Smokers
por: Graham, Amanda L, et al.
Publicado: (2008)

Extensive skin necrosis
por: Kurta, Anastasia O., et al.
Publicado: (2018)

The impact of maternal asthma on the preterm infants' gut metabolome and microbiome (MAP study)
por: Bai-Tong, Shiyu S., et al.
Publicado: (2022)

Letheon Administered in a Case of Labor
por: Keep, N. C.
Publicado: (1847)

Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking
por: Martin H., Christian, et al.
Publicado: (2019)

Translating metabolic exchange with imaging mass spectrometry
por: Yang, Yu-Liang, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_c73vbb670ivktthu2ffqo7lldh