Cargando…

Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors in a Neurofibromin-Dependent Manner

Neurofibromatosis type 1 (NF1) is among the most common neurogenic disorders, characterized by loss of function mutations in the neurofibromin gene (NF1). NF1 patients are extremely susceptible to developing neurofibromas, which can transform into deadly malignant peripheral nerve sheath tumors (MPN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alewine, Garrett, Knight, Jerrica, Ghantae, Adithya, Mamrega, Christina, Attiah, Bashnona, Coover, Robert A., Fahrenholtz, Cale D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321475/ https://www.ncbi.nlm.nih.gov/pubmed/35887576 http://dx.doi.org/10.3390/jpm12071080

Ejemplares similares

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors
por: Kahen, Elliot John, et al.
Publicado: (2018)

Malignant Peripheral Nerve Sheath Tumor Arising from Neurofibromatosis
por: Lee, Dae-Sung, et al.
Publicado: (2013)

Malignant Peripheral Nerve Sheath Tumors in Children with Neurofibromatosis Type 1
por: Pourtsidis, Apostolos, et al.
Publicado: (2014)

Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1
por: Chohan, Harleen, et al.
Publicado: (2018)

Malignant peripheral nerve sheath tumour in a patient with a plexiform neurofibromatosis
por: Nekkanti, Ravi, et al.
Publicado: (2015)

Cranial nerve and intramedullary spinal malignant peripheral nerve sheath tumor associated with neurofibromatosis-1
por: Newell, Christopher, et al.
Publicado: (2021)

Intraoral presentation of multiple malignant peripheral nerve sheath tumors associated with neurofibromatosis-1
por: Janardhanan, Mahija, et al.
Publicado: (2011)

Huge Intrathoracic Malignant Peripheral Nerve Sheath Tumor in an Adolescent with Neurofibromatosis Type 1
por: Yoon, Jong Hyung, et al.
Publicado: (2014)

Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1
por: Thomas, Laura, et al.
Publicado: (2012)

Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumor in the Nasal Cavity
por: Marini, Katerina, et al.
Publicado: (2023)

A Novel Frameshift Mutation in Neurofibromin 1 Gene in a Chinese Family with Neurofibromatosis Type 1
por: Dong, Ying-Ying, et al.
Publicado: (2017)

Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors
por: Park, Su-Jin, et al.
Publicado: (2013)

Malignant Peripheral Nerve Sheath Tumor of Non-Neurofibromatosis Type I Metastasized to the Cerebrospinal Axis
por: Park, Man-Kyu, et al.
Publicado: (2013)

Intraosseous malignant peripheral nerve sheath tumor of the sacrum in a patient with neurofibromatosis type I
por: Davila, Anthony, et al.
Publicado: (2019)

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors
por: Amirnasr, Azadeh, et al.
Publicado: (2020)

An Unusual Cause of Adrenal Mass in Neurofibromatosis Type 1: Malignant Peripheral Nerve Sheath Tumor
por: Shahait, Awni, et al.
Publicado: (2022)

Plexiform neurofibromatosis with peripheral malignant nerve sheath tumor and scoliosis - more surveillance imaging needed?()
por: Kamaludin, Siti Nurhazwani, et al.
Publicado: (2022)

Image-Based Differentiation of Benign and Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
por: Liu, Jun, et al.
Publicado: (2022)

Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization
por: Young, Lucy C., et al.
Publicado: (2023)

Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis Type I : Unusual Presentation of Intraabdominal or Intrathoracic Mass
por: Kim, Jong Gwang, et al.
Publicado: (2005)

Radiation Therapy in Management of Sporadic and Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors
por: Kahn, Jenna, et al.
Publicado: (2014)

Neurofibromatosis type 1‐associated malignant peripheral nerve sheath tumour carcinomatous pleurisy: an autopsy case
por: Furukawa, Marie, et al.
Publicado: (2019)

Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
por: Milković Periša, Marija, et al.
Publicado: (2017)

Neurofibromatosis type I with malignant peripheral nerve sheath tumors in the upper arm: A case report
por: Zhang, Lili, et al.
Publicado: (2019)

Pseudoprogression of Malignant Peripheral Nerve Sheath Tumor in Patient with Neurofibromatosis Type 1, a Case Report
por: Lessing, Andrés J., et al.
Publicado: (2021)

Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma
por: Mattox, Austin K, et al.
Publicado: (2022)

Metastatic Malignant Peripheral Nerve Sheath Tumor (MPNST) in Neurofibromatosis Type 1: Challenges in Diagnosis and Management
por: Pulliam, Steven, et al.
Publicado: (2022)

Neurofibromin Structure, Functions and Regulation
por: Bergoug, Mohammed, et al.
Publicado: (2020)

Identification of Germinal Neurofibromin Hotspots
por: Lois, Sergio, et al.
Publicado: (2022)

Heterogeneous Responses of Ovarian Cancer Cells to Silver Nanoparticles as a Single Agent and in Combination with Cisplatin
por: Fahrenholtz, Cale D., et al.
Publicado: (2017)

Malignant peripheral nerve sheath tumor associated with neurofibromatosis type 1, with metastasis to the heart: a case report
por: Kitamura, Masanori, et al.
Publicado: (2010)

Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
por: Kolberg, Matthias, et al.
Publicado: (2013)

Chemotherapy for the treatment of malignant peripheral nerve sheath tumors in neurofibromatosis 1: a 10-year institutional review
por: Zehou, Ouidad, et al.
Publicado: (2013)

An intraosseous malignant peripheral nerve sheath tumor of the lumbar spine without neurofibromatosis: Case report and review of the literature
por: SUZUKI, KAYO, et al.
Publicado: (2014)

A Case Report of a Malignant Peripheral Nerve Sheath Tumor of the Oral Cavity in Neurofibromatosis Type 1
por: Öztürk, Özmen, et al.
Publicado: (2012)

Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report
por: Tosun, Hacı Bayram, et al.
Publicado: (2015)

Outcomes of Treatment for Malignant Peripheral Nerve Sheath Tumors: Different Clinical Features Associated with Neurofibromatosis Type 1
por: Hwang, In Kyung, et al.
Publicado: (2017)

Subperiosteal hemorrhage: A rare complication in neurofibromatosis which may mimic malignant peripheral nerve sheath tumor
por: Thacker, Paul G., et al.
Publicado: (2019)

Neurofibromatosis type I-associated malignant peripheral nerve sheath tumors: a case report and literature review
por: Wu, Yibo, et al.
Publicado: (2020)

Neurofibromin Deficiency Causes Epidermal Growth Factor Receptor Upregulation through the Activation of Ras/ERK/SP1 Signaling Pathway in Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheet Tumor
por: Park, Gun-Hoo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vq2fmlrmdprvlm96594k9e9il2