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Impact of DNA damage response defects in cancer cells on response to immunotherapy and radiotherapy

The DNA damage response (DDR) is a complex set of downstream pathways triggered in response to DNA damage to maintain genomic stability. Many tumours exhibit mutations which inactivate components of the DDR, making them prone to the accumulation of DNA defects. These can both facilitate the developm...

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Detalles Bibliográficos
Autores principales:	Czajkowski, Daniel, Szmyd, Radosław, Gee, Harriet E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RADIATION ONCOLOGY
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321602/ https://www.ncbi.nlm.nih.gov/pubmed/35460184 http://dx.doi.org/10.1111/1754-9485.13413

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