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Evolution from a first clinical demyelinating event to multiple sclerosis in the REFLEX trial: Regional susceptibility in the conversion to multiple sclerosis at disease onset and its amenability to subcutaneous interferon beta‐1a
BACKGROUND AND PURPOSE: In the REFLEX trial (ClinicalTrials.gov identifier: NCT00404352), patients with a first clinical demyelinating event (FCDE) displayed significantly delayed onset of multiple sclerosis (MS; McDonald criteria) when treated with subcutaneous interferon beta‐1a (sc IFN β‐1a) vers...
Autores principales: | Battaglini, Marco, Vrenken, Hugo, Tappa Brocci, Riccardo, Gentile, Giordano, Luchetti, Ludovico, Versteeg, Adriaan, Freedman, Mark S., Uitdehaag, Bernard M. J., Kappos, Ludwig, Comi, Giancarlo, Seitzinger, Andrea, Jack, Dominic, Sormani, Maria Pia, Barkhof, Frederik, De Stefano, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321632/ https://www.ncbi.nlm.nih.gov/pubmed/35274413 http://dx.doi.org/10.1111/ene.15314 |
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