Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma

Modifications in nuclear structures of cells are implicated in several diseases including cancer. They result in changes in nuclear activity, structural dynamics and cell signalling. However, the role of the nuclear lamina and related proteins in malignant melanoma is still unknown. Its molecular ch...

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Detalles Bibliográficos
Autores principales: Lämmerhirt, Lisa, Kappelmann-Fenzl, Melanie, Fischer, Stefan, Pommer, Michaela, Zimmermann, Tom, Kluge, Viola, Matthies, Alexander, Kuphal, Silke, Bosserhoff, Anja Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321645/
https://www.ncbi.nlm.nih.gov/pubmed/35883595
http://dx.doi.org/10.3390/cells11142154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321645/
https://www.ncbi.nlm.nih.gov/pubmed/35883595
http://dx.doi.org/10.3390/cells11142154

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