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Promising Therapeutic Approach for SARS‐CoV‐2 Infections by Using a Rutin‐Based Combination Therapy

The development of new therapeutic approaches for SARS‐CoV‐2 infections is of particular current importance. The combination therapy proposed here is based on already proven, safe and inexpensive compounds. The natural compound rutin, one of the six therapy components, has the potential to inhibit b...

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Detalles Bibliográficos
Autor principal: Mazik, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321678/
https://www.ncbi.nlm.nih.gov/pubmed/35489042
http://dx.doi.org/10.1002/cmdc.202200157
Descripción
Sumario:The development of new therapeutic approaches for SARS‐CoV‐2 infections is of particular current importance. The combination therapy proposed here is based on already proven, safe and inexpensive compounds. The natural compound rutin, one of the six therapy components, has the potential to inhibit both viral and host cell targets. In addition, this therapy involves the use of acetylsalicylic acid, vitamin C and vitamin D(3), which should be administered together with calcium and magnesium. The importance of each component is briefly described in this article. Due to multiple anti‐infective properties of rutin, it provides a basis for combating a SARS‐CoV‐2 infection as well as various viral and bacterial co‐infections. There are strong indications for a good effect of this simple combination therapy, especially in the early stages of infection. It has the potential to be of interest both prophylactically and therapeutically, and offers the possibility of protection against severe disease progression.