Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis

By limiting the nitrogen source to glutamic acid, we isolated cyclic peptides from Euglena gracilis containing asparagine and non‐proteinogenic amino acids. Structure elucidation was accomplished through spectroscopic methods, mass spectrometry and chemical degradation. The euglenatides potently inh...

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Detalles Bibliográficos
Autores principales: Aldholmi, Mohammed, Ahmad, Rizwan, Carretero‐Molina, Daniel, Pérez‐Victoria, Ignacio, Martín, Jesús, Reyes, Fernando, Genilloud, Olga, Gourbeyre, Léa, Gefflaut, Thierry, Carlsson, Hanne, Maklakov, Alexei, O'Neill, Ellis, Field, Robert A., Wilkinson, Barrie, O'Connell, Maria, Ganesan, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321709/
https://www.ncbi.nlm.nih.gov/pubmed/35325497
http://dx.doi.org/10.1002/anie.202203175

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