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Deficits in rate of force production during multifinger tasks are associated with cognitive status
OBJECTIVES: The multifinger force deficit (MFFD) is the decline in force generated by an individual finger as the number of fingers contributing to the action is increased. It has been proposed that as a measure of neural sufficiency rather than muscle status, it provides a means of detecting indivi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321751/ https://www.ncbi.nlm.nih.gov/pubmed/35586946 http://dx.doi.org/10.1002/gps.5732 |
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author | Carson, Richard G. Holton, Eimíle |
author_facet | Carson, Richard G. Holton, Eimíle |
author_sort | Carson, Richard G. |
collection | PubMed |
description | OBJECTIVES: The multifinger force deficit (MFFD) is the decline in force generated by an individual finger as the number of fingers contributing to the action is increased. It has been proposed that as a measure of neural sufficiency rather than muscle status, it provides a means of detecting individuals at risk of cognitive decline. Age‐related deficits in central neural drive exert a disproportionate impact on the rate at which force can be generated. We examined whether a MFFD derived from the maximum rate at which force is generated, is more sensitive to individual differences in cognitive status, than one calculated using the maximum level of force. METHODS: Monotonic associations between each of two variants of the MFFD, and cognition (measured with the Montreal Cognitive Assessment), were estimated cross sectionally using generalized partial rank correlations, in which age, level of education and degree of handedness were included as covariates. The participants (n=26) were community dwelling adults aged 66‐87. RESULTS: The MFFD derived using the maximum rate of force development was negatively associated with cognitive status. The association for the MFFD based on the maximum level of force, was not statistically reliable. The associations with cognitive status obtained for both variants of the MFFD were of greater magnitude than those reported previously for standard grip strength dynamometry. CONCLUSION: The sensitivity with which the MFFD detects risk of cognitive decline may be enhanced by using the maximum rate of force developed by each finger, rather than the maximum force generated by each finger. |
format | Online Article Text |
id | pubmed-9321751 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93217512022-07-30 Deficits in rate of force production during multifinger tasks are associated with cognitive status Carson, Richard G. Holton, Eimíle Int J Geriatr Psychiatry Research Article OBJECTIVES: The multifinger force deficit (MFFD) is the decline in force generated by an individual finger as the number of fingers contributing to the action is increased. It has been proposed that as a measure of neural sufficiency rather than muscle status, it provides a means of detecting individuals at risk of cognitive decline. Age‐related deficits in central neural drive exert a disproportionate impact on the rate at which force can be generated. We examined whether a MFFD derived from the maximum rate at which force is generated, is more sensitive to individual differences in cognitive status, than one calculated using the maximum level of force. METHODS: Monotonic associations between each of two variants of the MFFD, and cognition (measured with the Montreal Cognitive Assessment), were estimated cross sectionally using generalized partial rank correlations, in which age, level of education and degree of handedness were included as covariates. The participants (n=26) were community dwelling adults aged 66‐87. RESULTS: The MFFD derived using the maximum rate of force development was negatively associated with cognitive status. The association for the MFFD based on the maximum level of force, was not statistically reliable. The associations with cognitive status obtained for both variants of the MFFD were of greater magnitude than those reported previously for standard grip strength dynamometry. CONCLUSION: The sensitivity with which the MFFD detects risk of cognitive decline may be enhanced by using the maximum rate of force developed by each finger, rather than the maximum force generated by each finger. John Wiley and Sons Inc. 2022-05-19 2022-06 /pmc/articles/PMC9321751/ /pubmed/35586946 http://dx.doi.org/10.1002/gps.5732 Text en © 2022 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Article Carson, Richard G. Holton, Eimíle Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title | Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title_full | Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title_fullStr | Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title_full_unstemmed | Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title_short | Deficits in rate of force production during multifinger tasks are associated with cognitive status |
title_sort | deficits in rate of force production during multifinger tasks are associated with cognitive status |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321751/ https://www.ncbi.nlm.nih.gov/pubmed/35586946 http://dx.doi.org/10.1002/gps.5732 |
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