Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation

Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown various antitumor properties. Herein, we investigated the influence of melatonin therapy on energy metabolism and mitochondrial integrity in SKOV-3 cells and tested whether its effects depended on MT1 receptor act...

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Detalles Bibliográficos
Autores principales: Cucielo, Maira Smaniotto, Cesário, Roberta Carvalho, Silveira, Henrique Spaulonci, Gaiotte, Letícia Barbosa, dos Santos, Sérgio Alexandre Alcantara, de Campos Zuccari, Debora Aparecida Pires, Seiva, Fábio Rodrigues Ferreira, Reiter, Russel J., de Almeida Chuffa, Luiz Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321770/
https://www.ncbi.nlm.nih.gov/pubmed/35889222
http://dx.doi.org/10.3390/molecules27144350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321770/
https://www.ncbi.nlm.nih.gov/pubmed/35889222
http://dx.doi.org/10.3390/molecules27144350

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