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Multi‐omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa
Metabolic resistance to pyrethroids is a menace to the continued effectiveness of malaria vector controls. Its molecular basis is complex and varies geographically across Africa. Here, we used a multi‐omics approach, followed‐up with functional validation to show that a directionally selected haplot...
Autores principales: | Hearn, Jack, Djoko Tagne, Carlos S., Ibrahim, Sulaiman S., Tene‐Fossog, Billy, Mugenzi, Leon M. J., Irving, Helen, Riveron, Jacob M., Weedall, Gareth D., Wondji, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321817/ https://www.ncbi.nlm.nih.gov/pubmed/35546741 http://dx.doi.org/10.1111/mec.16497 |
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