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Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach

Pyoderma gangrenosum (PG) is a rare, chronic inflammatory noninfectious dermatosis. It is associated with underlying systemic or hematological diseases such as myelodysplastic syndrome (MDS) and can be triggered after surgery. Recognition and diagnosis of PG can be difficult as it can mimic a wound...

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Autores principales: ten Dam, Lotte, ten Broeke, Miarca, Poot, Angelique M., Gilbers, Martijn D., Halfwerk, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321867/
https://www.ncbi.nlm.nih.gov/pubmed/35524433
http://dx.doi.org/10.1111/jocs.16570
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author ten Dam, Lotte
ten Broeke, Miarca
Poot, Angelique M.
Gilbers, Martijn D.
Halfwerk, Frank R.
author_facet ten Dam, Lotte
ten Broeke, Miarca
Poot, Angelique M.
Gilbers, Martijn D.
Halfwerk, Frank R.
author_sort ten Dam, Lotte
collection PubMed
description Pyoderma gangrenosum (PG) is a rare, chronic inflammatory noninfectious dermatosis. It is associated with underlying systemic or hematological diseases such as myelodysplastic syndrome (MDS) and can be triggered after surgery. Recognition and diagnosis of PG can be difficult as it can mimic a wound infection. Misdiagnosis could lead to invasive procedures which worsen the disease and have possible disastrous aftermath. A 74‐year‐old male with a history of MDS presents with an atypical sternal wound inflammation. Diagnosis confirmed PG after skin biopsy. No surgical or invasive procedures were performed and the patient was treated on an outpatient basis with prednisolone, clobetasol cream, and cyclosporine. This case shows the importance of a rapid diagnosis of the disease. Awareness is required for the diagnosis of PG in a wound with pronounced livid borders, without improvement after antibiotic treatment or worsening after debridement. Rapid diagnosis and treatment reduce high healthcare costs, morbidity, and mortality.
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spelling pubmed-93218672022-07-30 Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach ten Dam, Lotte ten Broeke, Miarca Poot, Angelique M. Gilbers, Martijn D. Halfwerk, Frank R. J Card Surg Case Reports Pyoderma gangrenosum (PG) is a rare, chronic inflammatory noninfectious dermatosis. It is associated with underlying systemic or hematological diseases such as myelodysplastic syndrome (MDS) and can be triggered after surgery. Recognition and diagnosis of PG can be difficult as it can mimic a wound infection. Misdiagnosis could lead to invasive procedures which worsen the disease and have possible disastrous aftermath. A 74‐year‐old male with a history of MDS presents with an atypical sternal wound inflammation. Diagnosis confirmed PG after skin biopsy. No surgical or invasive procedures were performed and the patient was treated on an outpatient basis with prednisolone, clobetasol cream, and cyclosporine. This case shows the importance of a rapid diagnosis of the disease. Awareness is required for the diagnosis of PG in a wound with pronounced livid borders, without improvement after antibiotic treatment or worsening after debridement. Rapid diagnosis and treatment reduce high healthcare costs, morbidity, and mortality. John Wiley and Sons Inc. 2022-05-06 2022-08 /pmc/articles/PMC9321867/ /pubmed/35524433 http://dx.doi.org/10.1111/jocs.16570 Text en © 2022 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
ten Dam, Lotte
ten Broeke, Miarca
Poot, Angelique M.
Gilbers, Martijn D.
Halfwerk, Frank R.
Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title_full Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title_fullStr Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title_full_unstemmed Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title_short Noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: A no‐touch approach
title_sort noninfectious sternal wound inflammation after coronary artery bypass grafting in a patient with myelodysplastic syndrome: a no‐touch approach
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321867/
https://www.ncbi.nlm.nih.gov/pubmed/35524433
http://dx.doi.org/10.1111/jocs.16570
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