Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing

The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; howeve...

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Autores principales: Ji, Hezhao, Sandstrom, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321895/
https://www.ncbi.nlm.nih.gov/pubmed/35889985
http://dx.doi.org/10.3390/pathogens11070739
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author Ji, Hezhao
Sandstrom, Paul
author_facet Ji, Hezhao
Sandstrom, Paul
author_sort Ji, Hezhao
collection PubMed
description The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; however, the suitability and performance of these analytes in HIVDRT and the clinical relevance of the results from them may vary significantly. This article provides a focused overview of the performance, strengths, and weaknesses of various analytes while used in HIVDRT, which may inform the optimal analytes selection in different application contexts.
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spelling pubmed-93218952022-07-27 Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing Ji, Hezhao Sandstrom, Paul Pathogens Review The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; however, the suitability and performance of these analytes in HIVDRT and the clinical relevance of the results from them may vary significantly. This article provides a focused overview of the performance, strengths, and weaknesses of various analytes while used in HIVDRT, which may inform the optimal analytes selection in different application contexts. MDPI 2022-06-29 /pmc/articles/PMC9321895/ /pubmed/35889985 http://dx.doi.org/10.3390/pathogens11070739 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ji, Hezhao
Sandstrom, Paul
Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title_full Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title_fullStr Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title_full_unstemmed Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title_short Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
title_sort overview of the analytes applied in genotypic hiv drug resistance testing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321895/
https://www.ncbi.nlm.nih.gov/pubmed/35889985
http://dx.doi.org/10.3390/pathogens11070739
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