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Treating second‐relapsed/refractory first‐relapsed childhood acute myeloid leukaemia: Successful salvage rather than palliation?

Prognosis of second‐relapsed/refractory first‐relapsed childhood acute myeloid leukaemia remains poor and there are no clear guidelines on the best treatment approach. The report by White et al. suggests that, while outcomes are still unsatisfactory, there is room to pursue a curative approach rathe...

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Detalles Bibliográficos
Autor principal: Merli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321902/
https://www.ncbi.nlm.nih.gov/pubmed/35435248
http://dx.doi.org/10.1111/bjh.18140
Descripción
Sumario:Prognosis of second‐relapsed/refractory first‐relapsed childhood acute myeloid leukaemia remains poor and there are no clear guidelines on the best treatment approach. The report by White et al. suggests that, while outcomes are still unsatisfactory, there is room to pursue a curative approach rather than palliation. Commentary on: White et al. Clinical outcomes of second relapsed and refractory first relapsed paediatric AML: A retrospective study within the NOPHO‐DB SHIP consortium. Br J Haematol 2022;197:755‐765.