Liquid Biopsy with Detection of NRAS(Q61K) Mutation in Cerebrospinal Fluid: An Alternative Tool for the Diagnosis of Primary Pediatric Leptomeningeal Melanoma

Primary leptomeningeal melanoma (PLMM) is a very rare disease in childhood with a poor prognosis. NRAS(Q16K) mutation frequently drives malignant transformation in this population, so its evaluation should be considered in childhood PLMM diagnosis. In the presented case, the mutation was detected by...

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Detalles Bibliográficos
Autores principales: Mastronuzzi, Angela, Fabozzi, Francesco, Rinelli, Martina, De Vito, Rita, Agolini, Emanuele, Colafati, Giovanna Stefania, Cacchione, Antonella, Carai, Andrea, De Ioris, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321921/
https://www.ncbi.nlm.nih.gov/pubmed/35885515
http://dx.doi.org/10.3390/diagnostics12071609

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