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Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea

Background and Objectives: Poor sleep quality in patients with obstructive sleep apnea (OSA) may be associated with different clinical and polysomnographic features. The aim of this study was to identify features associated with poor sleep quality in OSA patients. Materials and Methods: This was a c...

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Autores principales: Kania, Aleksander, Polok, Kamil, Celejewska-Wójcik, Natalia, Nastałek, Paweł, Opaliński, Andrzej, Mrzygłód, Barbara, Regulski, Krzysztof, Głowacki, Mirosław, Sładek, Krzysztof, Bochenek, Grażyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321990/
https://www.ncbi.nlm.nih.gov/pubmed/35888626
http://dx.doi.org/10.3390/medicina58070907
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author Kania, Aleksander
Polok, Kamil
Celejewska-Wójcik, Natalia
Nastałek, Paweł
Opaliński, Andrzej
Mrzygłód, Barbara
Regulski, Krzysztof
Głowacki, Mirosław
Sładek, Krzysztof
Bochenek, Grażyna
author_facet Kania, Aleksander
Polok, Kamil
Celejewska-Wójcik, Natalia
Nastałek, Paweł
Opaliński, Andrzej
Mrzygłód, Barbara
Regulski, Krzysztof
Głowacki, Mirosław
Sładek, Krzysztof
Bochenek, Grażyna
author_sort Kania, Aleksander
collection PubMed
description Background and Objectives: Poor sleep quality in patients with obstructive sleep apnea (OSA) may be associated with different clinical and polysomnographic features. The aim of this study was to identify features associated with poor sleep quality in OSA patients. Materials and Methods: This was a cross-sectional study enrolling patients with OSA confirmed by polysomnography (PSG). In addition to gathering clinical data, patients were assessed using the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), and the Clinical Global Impression Scale. Univariate and multivariable analyses were performed to identify factors associated with an increased risk of poor sleep quality in this population. Results: Among 505 enrolled patients (mean age of 57.1 years, 69.7% male) poor quality of sleep (PSQI score ≥ 5) was confirmed in 68.9% of them. Multivariable analysis revealed the following factors associated with poor sleep quality: chronic heart failure (OR 3.111; 95% CI, 1.083–8.941, p = 0.035), male sex (OR 0.396; 95% CI, 0.199–0.787, p = 0.008), total ESS score (OR 1.193; 95% CI, 1.124–1.266, p < 0.001), minimal saturation during sleep (OR 1.034; 95% CI, 1.002–1.066, p = 0.036), and N3 percentage of total sleep time (OR 1.110; 95% CI, 1.027–1.200, p = 0.009). Conclusions: Our study suggests that both the female sex and coexistence of heart failure are independent risk factors for poor sleep quality. Moreover, we hypothesize that nocturnal hypoxia may lead to a misperception of sleep quality and may explain the counterintuitive association between a higher proportion of deep sleep and poor sleep quality.
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spelling pubmed-93219902022-07-27 Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea Kania, Aleksander Polok, Kamil Celejewska-Wójcik, Natalia Nastałek, Paweł Opaliński, Andrzej Mrzygłód, Barbara Regulski, Krzysztof Głowacki, Mirosław Sładek, Krzysztof Bochenek, Grażyna Medicina (Kaunas) Article Background and Objectives: Poor sleep quality in patients with obstructive sleep apnea (OSA) may be associated with different clinical and polysomnographic features. The aim of this study was to identify features associated with poor sleep quality in OSA patients. Materials and Methods: This was a cross-sectional study enrolling patients with OSA confirmed by polysomnography (PSG). In addition to gathering clinical data, patients were assessed using the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), and the Clinical Global Impression Scale. Univariate and multivariable analyses were performed to identify factors associated with an increased risk of poor sleep quality in this population. Results: Among 505 enrolled patients (mean age of 57.1 years, 69.7% male) poor quality of sleep (PSQI score ≥ 5) was confirmed in 68.9% of them. Multivariable analysis revealed the following factors associated with poor sleep quality: chronic heart failure (OR 3.111; 95% CI, 1.083–8.941, p = 0.035), male sex (OR 0.396; 95% CI, 0.199–0.787, p = 0.008), total ESS score (OR 1.193; 95% CI, 1.124–1.266, p < 0.001), minimal saturation during sleep (OR 1.034; 95% CI, 1.002–1.066, p = 0.036), and N3 percentage of total sleep time (OR 1.110; 95% CI, 1.027–1.200, p = 0.009). Conclusions: Our study suggests that both the female sex and coexistence of heart failure are independent risk factors for poor sleep quality. Moreover, we hypothesize that nocturnal hypoxia may lead to a misperception of sleep quality and may explain the counterintuitive association between a higher proportion of deep sleep and poor sleep quality. MDPI 2022-07-08 /pmc/articles/PMC9321990/ /pubmed/35888626 http://dx.doi.org/10.3390/medicina58070907 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kania, Aleksander
Polok, Kamil
Celejewska-Wójcik, Natalia
Nastałek, Paweł
Opaliński, Andrzej
Mrzygłód, Barbara
Regulski, Krzysztof
Głowacki, Mirosław
Sładek, Krzysztof
Bochenek, Grażyna
Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title_full Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title_fullStr Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title_full_unstemmed Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title_short Clinical and Polysomnographic Features Associated with Poor Sleep Quality in Patients with Obstructive Sleep Apnea
title_sort clinical and polysomnographic features associated with poor sleep quality in patients with obstructive sleep apnea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321990/
https://www.ncbi.nlm.nih.gov/pubmed/35888626
http://dx.doi.org/10.3390/medicina58070907
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