Improvement in Solubility–Permeability Interplay of Psoralens from Brosimum gaudichaudii Plant Extract upon Complexation with Hydroxypropyl-β-cyclodextrin

Psoralen (PSO) and 5-methoxypsoralen (5-MOP) are widely used drugs in oral photochemotherapy against vitiligo and major bioactive components of root bark extract of Brosimum gaudichaudii Trécul (EBGT), previously standardized by LC-MS. However, the exceptionally low water solubility of these psorale...

Descripción completa

Detalles Bibliográficos
Autores principales: Machado, Rúbia Darc, Silva, Júlio C. G., Silva, Luís A. D., Oliveira, Gerlon de A. R., Lião, Luciano M., Lima, Eliana M., de Morais, Mariana C., da Conceição, Edemilson C., Rezende, Kênnia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322082/
https://www.ncbi.nlm.nih.gov/pubmed/35889459
http://dx.doi.org/10.3390/molecules27144580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322082/
https://www.ncbi.nlm.nih.gov/pubmed/35889459
http://dx.doi.org/10.3390/molecules27144580

Ejemplares similares