Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors

For many inflammatory diseases, new effective drugs with fewer side effects are needed. While it appears promising to target the activation of the central pro-inflammatory transcription factor NF-κB, many previously discovered agents suffered from cytotoxicity. In this study, new alkylthiourea quina...

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Detalles Bibliográficos
Autores principales: Darwish, Sarah S., Chen, Po-Jen, Hamed, Mostafa M., Wagdy, Reem A., Chen, Shun-Hua, Abadi, Ashraf H., Abdel-Halim, Mohammad, Hwang, Tsong-Long, Engel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322122/
https://www.ncbi.nlm.nih.gov/pubmed/35890077
http://dx.doi.org/10.3390/ph15070778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322122/
https://www.ncbi.nlm.nih.gov/pubmed/35890077
http://dx.doi.org/10.3390/ph15070778

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