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Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors

For many inflammatory diseases, new effective drugs with fewer side effects are needed. While it appears promising to target the activation of the central pro-inflammatory transcription factor NF-κB, many previously discovered agents suffered from cytotoxicity. In this study, new alkylthiourea quina...

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Detalles Bibliográficos
Autores principales:	Darwish, Sarah S., Chen, Po-Jen, Hamed, Mostafa M., Wagdy, Reem A., Chen, Shun-Hua, Abadi, Ashraf H., Abdel-Halim, Mohammad, Hwang, Tsong-Long, Engel, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322122/ https://www.ncbi.nlm.nih.gov/pubmed/35890077 http://dx.doi.org/10.3390/ph15070778

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