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Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature

Short bowel syndrome (SBS) is a devastating disorder with both short- and long-term implications for patients. Unfortunately, the prevalence of SBS has doubled over the past 40 years. Broadly speaking, the etiology of SBS can be categorized as congenital or secondary, the latter typically due to ext...

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Autores principales: Muff, Julian L., Sokolovski, Filipp, Walsh-Korb, Zarah, Choudhury, Rashikh A., Dunn, James C. Y., Holland-Cunz, Stefan G., Vuille-dit-Bille, Raphael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322125/
https://www.ncbi.nlm.nih.gov/pubmed/35884008
http://dx.doi.org/10.3390/children9071024
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author Muff, Julian L.
Sokolovski, Filipp
Walsh-Korb, Zarah
Choudhury, Rashikh A.
Dunn, James C. Y.
Holland-Cunz, Stefan G.
Vuille-dit-Bille, Raphael N.
author_facet Muff, Julian L.
Sokolovski, Filipp
Walsh-Korb, Zarah
Choudhury, Rashikh A.
Dunn, James C. Y.
Holland-Cunz, Stefan G.
Vuille-dit-Bille, Raphael N.
author_sort Muff, Julian L.
collection PubMed
description Short bowel syndrome (SBS) is a devastating disorder with both short- and long-term implications for patients. Unfortunately, the prevalence of SBS has doubled over the past 40 years. Broadly speaking, the etiology of SBS can be categorized as congenital or secondary, the latter typically due to extensive small bowel resection following diseases of the small intestine, e.g., necrotizing enterocolitis, Hirschsprung’s disease or intestinal atresia. As of yet, no cure exists, thus, conservative treatment, primarily parenteral nutrition (PN), is the first-line therapy. In some cases, weaning from PN is not possible and operative therapy is required. The invention of the longitudinal intestinal lengthening and tailoring (LILT or Bianchi) procedure in 1980 was a major step forward in patient care and spawned further techniques that continue to improve lives for patients with severe SBS (e.g., double barrel enteroplasty, serial transverse enteroplasty, etc.). With this review, we aim to provide an overview of the clinical implications of SBS, common conservative therapies and the development of operative techniques over the past six decades. We also provide a short outlook on the future of operative techniques, specifically with respect to regenerative medicine.
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spelling pubmed-93221252022-07-27 Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature Muff, Julian L. Sokolovski, Filipp Walsh-Korb, Zarah Choudhury, Rashikh A. Dunn, James C. Y. Holland-Cunz, Stefan G. Vuille-dit-Bille, Raphael N. Children (Basel) Review Short bowel syndrome (SBS) is a devastating disorder with both short- and long-term implications for patients. Unfortunately, the prevalence of SBS has doubled over the past 40 years. Broadly speaking, the etiology of SBS can be categorized as congenital or secondary, the latter typically due to extensive small bowel resection following diseases of the small intestine, e.g., necrotizing enterocolitis, Hirschsprung’s disease or intestinal atresia. As of yet, no cure exists, thus, conservative treatment, primarily parenteral nutrition (PN), is the first-line therapy. In some cases, weaning from PN is not possible and operative therapy is required. The invention of the longitudinal intestinal lengthening and tailoring (LILT or Bianchi) procedure in 1980 was a major step forward in patient care and spawned further techniques that continue to improve lives for patients with severe SBS (e.g., double barrel enteroplasty, serial transverse enteroplasty, etc.). With this review, we aim to provide an overview of the clinical implications of SBS, common conservative therapies and the development of operative techniques over the past six decades. We also provide a short outlook on the future of operative techniques, specifically with respect to regenerative medicine. MDPI 2022-07-10 /pmc/articles/PMC9322125/ /pubmed/35884008 http://dx.doi.org/10.3390/children9071024 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Muff, Julian L.
Sokolovski, Filipp
Walsh-Korb, Zarah
Choudhury, Rashikh A.
Dunn, James C. Y.
Holland-Cunz, Stefan G.
Vuille-dit-Bille, Raphael N.
Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title_full Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title_fullStr Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title_full_unstemmed Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title_short Surgical Treatment of Short Bowel Syndrome—The Past, the Present and the Future, a Descriptive Review of the Literature
title_sort surgical treatment of short bowel syndrome—the past, the present and the future, a descriptive review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322125/
https://www.ncbi.nlm.nih.gov/pubmed/35884008
http://dx.doi.org/10.3390/children9071024
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