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Antibacterial activity of propolins from Taiwanese green propolis
Taiwanese green propolis is a prenylated flavonoid rich honeybee product and propolins isolated from Taiwanese green propolis exert a broad spectrum of biological activities, such as anti-cancer and anti-oxidant. However, the anti-bacterial effects of Taiwanese green propolis or propolins are still...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taiwan Food and Drug Administration
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322210/ https://www.ncbi.nlm.nih.gov/pubmed/29567247 http://dx.doi.org/10.1016/j.jfda.2017.10.002 |
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author | Chen, Yue-Wen Ye, Siou-Ru Ting, Chieh Yu, Yu-Hsiang |
author_facet | Chen, Yue-Wen Ye, Siou-Ru Ting, Chieh Yu, Yu-Hsiang |
author_sort | Chen, Yue-Wen |
collection | PubMed |
description | Taiwanese green propolis is a prenylated flavonoid rich honeybee product and propolins isolated from Taiwanese green propolis exert a broad spectrum of biological activities, such as anti-cancer and anti-oxidant. However, the anti-bacterial effects of Taiwanese green propolis or propolins are still poorly understood. In the current study, the antibacterial effects of Taiwanese green propolis and propolins were evaluated. Results show that the maximum dry matter yields of Taiwanese green propolis were observed in the 95% and 99.5% ethanol extracts compared to other extraction methods. Consistently, the highest concentration of propolins C, D, F and G from Taiwanese green propolis was obtained in 95% and 99.5% ethanol extracts. Propolins inhibited the growth of gram-positive bacterial strains (Staphylococcus aureus, Bacillus subtilis, Listeria monocytogenes and Paenibacillus larvae). The average minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of propolins from ethanol extracts were 20 μg/ml. Among the propolins, propolin C had the highest antibacterial activity. Furthermore, Taiwanese green propolis also showed antibacterial activity against methicillin-resistant S. aureus (MRSA). In conclusion, these results demonstrate that Taiwanese green propolis and propolins have significant antibacterial activity, particularly against gram-positive bacterial strains. |
format | Online Article Text |
id | pubmed-9322210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Taiwan Food and Drug Administration |
record_format | MEDLINE/PubMed |
spelling | pubmed-93222102022-08-09 Antibacterial activity of propolins from Taiwanese green propolis Chen, Yue-Wen Ye, Siou-Ru Ting, Chieh Yu, Yu-Hsiang J Food Drug Anal Original Article Taiwanese green propolis is a prenylated flavonoid rich honeybee product and propolins isolated from Taiwanese green propolis exert a broad spectrum of biological activities, such as anti-cancer and anti-oxidant. However, the anti-bacterial effects of Taiwanese green propolis or propolins are still poorly understood. In the current study, the antibacterial effects of Taiwanese green propolis and propolins were evaluated. Results show that the maximum dry matter yields of Taiwanese green propolis were observed in the 95% and 99.5% ethanol extracts compared to other extraction methods. Consistently, the highest concentration of propolins C, D, F and G from Taiwanese green propolis was obtained in 95% and 99.5% ethanol extracts. Propolins inhibited the growth of gram-positive bacterial strains (Staphylococcus aureus, Bacillus subtilis, Listeria monocytogenes and Paenibacillus larvae). The average minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of propolins from ethanol extracts were 20 μg/ml. Among the propolins, propolin C had the highest antibacterial activity. Furthermore, Taiwanese green propolis also showed antibacterial activity against methicillin-resistant S. aureus (MRSA). In conclusion, these results demonstrate that Taiwanese green propolis and propolins have significant antibacterial activity, particularly against gram-positive bacterial strains. Taiwan Food and Drug Administration 2017-11-10 /pmc/articles/PMC9322210/ /pubmed/29567247 http://dx.doi.org/10.1016/j.jfda.2017.10.002 Text en © 2018 Taiwan Food and Drug Administration https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Original Article Chen, Yue-Wen Ye, Siou-Ru Ting, Chieh Yu, Yu-Hsiang Antibacterial activity of propolins from Taiwanese green propolis |
title | Antibacterial activity of propolins from Taiwanese green propolis |
title_full | Antibacterial activity of propolins from Taiwanese green propolis |
title_fullStr | Antibacterial activity of propolins from Taiwanese green propolis |
title_full_unstemmed | Antibacterial activity of propolins from Taiwanese green propolis |
title_short | Antibacterial activity of propolins from Taiwanese green propolis |
title_sort | antibacterial activity of propolins from taiwanese green propolis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322210/ https://www.ncbi.nlm.nih.gov/pubmed/29567247 http://dx.doi.org/10.1016/j.jfda.2017.10.002 |
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