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Stability-indicating spectrofluorimetric method with enhanced sensitivity for determination of vancomycin hydrochloride in pharmaceuticals and spiked human plasma: Application to degradation kinetics

Based on investigating the relative fluorescence intensity of vancomycin hydrochloride (VCM) in methanol, a simple, highly sensitive, time-saving and specific spectrofluorimetric method was developed and validated. VCM fluorescence was measured at 335 nm when excited at 268 nm. Excellent linearity i...

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Detalles Bibliográficos
Autores principales: El-Din, Mohie Khaled Sharaf, Ibrahim, Fawzia, El-Deen, Asmaa Kamal, Shimizu, Kuniyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322213/
https://www.ncbi.nlm.nih.gov/pubmed/29567255
http://dx.doi.org/10.1016/j.jfda.2017.06.005

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