Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model

Many controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes to investigate whether long term (90 days) aspartame (40 mg/kg b.wt) administration could induce oxidative stress and alter the memory in Wi...

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Detalles Bibliográficos
Autores principales: Iyaswamy, Ashok, Kammella, Ananth Kumar, Thavasimuthu, Citarasu, Wankupar, Wankhar, Dapkupar, Wankhar, Shanmugam, Sambantham, Rajan, Ravindran, Rathinasamy, Sheeladevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322224/
https://www.ncbi.nlm.nih.gov/pubmed/29567262
http://dx.doi.org/10.1016/j.jfda.2017.11.001

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