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NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia

Hypoxia exerts broad effects on cardiomyocyte function and viability, ranging from altered metabolism and mitochondrial physiology to apoptotic or necrotic cell death. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a key regulator of...

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Detalles Bibliográficos
Autores principales: Rabinovich-Nikitin, Inna, Blant, Alexandra, Dhingra, Rimpy, Kirshenbaum, Lorrie A., Czubryt, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322255/
https://www.ncbi.nlm.nih.gov/pubmed/35883637
http://dx.doi.org/10.3390/cells11142193

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