Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell markers

Cancer stem cells (CSCs) virtually present in all tumors albeit in small numbers are primarily responsible for driving cancer progression, metastasis, drug resistance, and recurrence. Prostate cancer (PCa) is the second most frequent cancer in men worldwide, and castration resistant prostate cancer...

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Detalles Bibliográficos
Autores principales: Thomas, Elizabeth, Thankan, Retheesh S., Purushottamachar, Puranik, Huang, Weiliang, Kane, Maureen A., Zhang, Yuji, Ambulos, Nicholas, Weber, David J., Njar, Vincent C. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322274/
https://www.ncbi.nlm.nih.gov/pubmed/35512605
http://dx.doi.org/10.1002/mc.23406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322274/
https://www.ncbi.nlm.nih.gov/pubmed/35512605
http://dx.doi.org/10.1002/mc.23406

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