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Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers

AIM: We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. METHODS: Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well‐being (Danish))....

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Autores principales: Berglund, Nanna R., Lewis, Jack I., Michaelsen, Kim F., Mølgaard, Christian, Renault, Kristina M., Carlsen, Emma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322285/
https://www.ncbi.nlm.nih.gov/pubmed/35357724
http://dx.doi.org/10.1111/apa.16346
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author Berglund, Nanna R.
Lewis, Jack I.
Michaelsen, Kim F.
Mølgaard, Christian
Renault, Kristina M.
Carlsen, Emma M.
author_facet Berglund, Nanna R.
Lewis, Jack I.
Michaelsen, Kim F.
Mølgaard, Christian
Renault, Kristina M.
Carlsen, Emma M.
author_sort Berglund, Nanna R.
collection PubMed
description AIM: We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. METHODS: Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well‐being (Danish)). Body composition at birth and at 3 years was assessed by dual‐energy X‐ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years. RESULTS: Birthweight z‐score (BWZ) was positively associated with fat‐free mass (FFM), height, fat‐free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years. CONCLUSION: We showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health.
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spelling pubmed-93222852022-07-30 Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers Berglund, Nanna R. Lewis, Jack I. Michaelsen, Kim F. Mølgaard, Christian Renault, Kristina M. Carlsen, Emma M. Acta Paediatr Original Articles & Brief Reports AIM: We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. METHODS: Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well‐being (Danish)). Body composition at birth and at 3 years was assessed by dual‐energy X‐ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years. RESULTS: Birthweight z‐score (BWZ) was positively associated with fat‐free mass (FFM), height, fat‐free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years. CONCLUSION: We showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health. John Wiley and Sons Inc. 2022-04-05 2022-07 /pmc/articles/PMC9322285/ /pubmed/35357724 http://dx.doi.org/10.1111/apa.16346 Text en © 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles & Brief Reports
Berglund, Nanna R.
Lewis, Jack I.
Michaelsen, Kim F.
Mølgaard, Christian
Renault, Kristina M.
Carlsen, Emma M.
Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title_full Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title_fullStr Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title_full_unstemmed Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title_short Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
title_sort birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in danish children born from obese mothers
topic Original Articles & Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322285/
https://www.ncbi.nlm.nih.gov/pubmed/35357724
http://dx.doi.org/10.1111/apa.16346
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