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Lactate saturation limits bicarbonate detection in hyperpolarized (13)C‐pyruvate MRI of the brain

PURPOSE: To investigate the potential effects of [1‐(13)C]lactate RF saturation pulses on [(13)C]bicarbonate detection in hyperpolarized [1‐(13)C]pyruvate MRI of the brain. METHODS: Thirteen healthy rats underwent MRI with hyperpolarized [1‐(13)C]pyruvate of either the brain (n = 8) or the kidneys,...

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Detalles Bibliográficos
Autores principales: Bøgh, Nikolaj, Grist, James T., Rasmussen, Camilla W., Bertelsen, Lotte B., Hansen, Esben S. S., Blicher, Jakob U., Tyler, Damian J., Laustsen, Christoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322338/
https://www.ncbi.nlm.nih.gov/pubmed/35533254
http://dx.doi.org/10.1002/mrm.29290