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Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways
P2RX7, an ionotropic receptor for extracellular adenosine triphosphate (ATP), is expressed on immune cells, including macrophages, monocytes, and dendritic cells and is upregulated on nonimmune cells following injury. P2RX7 plays a role in many biological processes, including production of proinflam...
Autores principales: | Prendecki, Maria, McAdoo, Stephen P, Turner‐Stokes, Tabitha, Garcia‐Diaz, Ana, Orriss, Isabel, Woollard, Kevin J, Behmoaras, Jacques, Cook, H Terence, Unwin, Robert, Pusey, Charles D, Aitman, Timothy J, Tam, Frederick WK |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322550/ https://www.ncbi.nlm.nih.gov/pubmed/35239186 http://dx.doi.org/10.1002/path.5890 |
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