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Central Role of Semaphorin 3B in a Serum‐Induced Arthritis Model and Reduced Levels in Patients With Rheumatoid Arthritis

OBJECTIVE: Semaphorin 3B (Sema3B) decreases the migratory and invasive capacities of fibroblast‐like synoviocytes (FLS) in rheumatoid arthritis (RA) and suppresses expression of matrix metalloproteinases. We undertook this study to examine the role of Sema3B in a mouse model of arthritis and its exp...

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Detalles Bibliográficos
Autores principales:	Igea, Ana, Carvalheiro, Tiago, Malvar‐Fernández, Beatriz, Martinez‐Ramos, Sara, Rafael‐Vidal, Carlos, Niemantsverdriet, Ellis, Varadé, Jezabel, Fernández‐Carrera, Andrea, Jimenez, Norman, McGarry, Trudy, Rodriguez‐Trillo, Angela, Veale, Douglas, Fearon, Ursula, Conde, Carmen, Pego‐Reigosa, Jose M., González‐Fernández, África, Reedquist, Kris A., Radstake, Timothy R. D. J., van der Helm‐Van Mil, Annette, García, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Periodicals, Inc. 2022
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322571/ https://www.ncbi.nlm.nih.gov/pubmed/35001548 http://dx.doi.org/10.1002/art.42065

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