Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape

Defective DNA mismatch repair (dMMR) causes elevated tumour mutational burden (TMB) and microsatellite instability (MSI) in multiple cancer types. dMMR/MSI colorectal cancers (CRCs) have enhanced T‐cell infiltrate and favourable outcome; however, this association has not been reliably detected in ot...

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Detalles Bibliográficos
Autores principales: Glaire, Mark A, Ryan, Neil AJ, Ijsselsteijn, Marieke E, Kedzierska, Katarzyna, Obolenski, Sofia, Ali, Reem, Crosbie, Emma J, Bosse, Tjalling, de Miranda, Noel FCC, Church, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322587/
https://www.ncbi.nlm.nih.gov/pubmed/35262923
http://dx.doi.org/10.1002/path.5894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322587/
https://www.ncbi.nlm.nih.gov/pubmed/35262923
http://dx.doi.org/10.1002/path.5894

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