Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer’s Disease Patients

Background: Aβ(42) deposition plays a pivotal role in AD pathogenesis by inducing the activation of microglial cells and neuroinflammation. This process is antagonized by microglia-mediated clearance of Aβ plaques. Activation of the NLRP3 inflammasome is involved in neuroinflammation and in the impa...

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Detalles Bibliográficos
Autores principales: La Rosa, Francesca, Zoia, Chiara Paola, Bazzini, Chiara, Bolognini, Alessandra, Saresella, Marina, Conti, Elisa, Ferrarese, Carlo, Piancone, Federica, Marventano, Ivana, Galimberti, Daniela, Fenoglio, Chiara, Scarpini, Elio, Clerici, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322713/
https://www.ncbi.nlm.nih.gov/pubmed/35883623
http://dx.doi.org/10.3390/cells11142180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322713/
https://www.ncbi.nlm.nih.gov/pubmed/35883623
http://dx.doi.org/10.3390/cells11142180

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