Suppression of Ribose-5-Phosphate Isomerase a Induces ROS to Activate Autophagy, Apoptosis, and Cellular Senescence in Lung Cancer

Ribose-5-phosphate isomerase A (RPIA) regulates tumorigenesis in liver and colorectal cancer. However, the role of RPIA in lung cancer remains obscure. Here we report that the suppression of RPIA diminishes cellular proliferation and activates autophagy, apoptosis, and cellular senescence in lung ca...

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Detalles Bibliográficos
Autores principales: Nieh, Yu-Chin, Chou, Yu-Ting, Wang, Chao-Yung, Lin, Shi-Xian, Ciou, Shih-Ci, Yuh, Chiou-Hwa, Wang, Horng-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322731/
https://www.ncbi.nlm.nih.gov/pubmed/35887232
http://dx.doi.org/10.3390/ijms23147883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322731/
https://www.ncbi.nlm.nih.gov/pubmed/35887232
http://dx.doi.org/10.3390/ijms23147883

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