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Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus Monkeys
PURPOSE: Neutralizing antibodies, administrated through intravenous infusion, have shown to be highly efficacious in treating mild and moderate COVID-19 caused by SARS-CoV-2 infection in the lung. However, antibodies do not transport across the plasma-lung barrier efficiently, and up to 100 mg/kg do...
Autores principales: | Jia, Jilei, Yin, Zhaojuan, Zhang, Xiao, Li, Huimin, Meng, Dan, Liu, Qianqian, Wang, Hongfang, Han, Meng, Suo, Shixiang, Liu, Yan, Hu, Ping, Sun, Chunyun, Li, Jing, Xie, Liangzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322739/ https://www.ncbi.nlm.nih.gov/pubmed/35882740 http://dx.doi.org/10.1007/s11095-022-03340-9 |
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