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Epithelial–Mesenchymal Transition Suppresses AMPK and Sensitizes Cancer Cells to Pyroptosis under Energy Stress

Epithelial–mesenchymal transition (EMT) is implicated in tumor metastasis and therapeutic resistance. It remains a challenge to target cancer cells that have undergone EMT. The Snail family of key EMT-inducing transcription factors directly binds to and transcriptionally represses not only epithelia...

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Detalles Bibliográficos
Autores principales: Liang, Mingwei, Li, Jennifer W., Luo, Huacheng, Lulu, Sarah, Calbay, Ozlem, Shenoy, Anitha, Tan, Ming, Law, Brian K., Huang, Shuang, Xiao, Tsan Sam, Chen, Hao, Wu, Lizi, Chang, Jia, Lu, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322750/
https://www.ncbi.nlm.nih.gov/pubmed/35883651
http://dx.doi.org/10.3390/cells11142208