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MiR-155 Dysregulation Is Associated with the Augmentation of ROS/p53 Axis of Fibrosis in Thioacetamide-Induced Hepatotoxicity and Is Protected by Resveratrol

Liver fibrosis is a hallmark of thioacetamide (TAA) intoxications. MicroRNAs (miRs), such as miR-155, have been implied in the pathogenesis of liver disease, and regulated by the antioxidant and anti-inflammatory compound resveratrol (RES). The link between reactive oxygen species (ROS), tumour supp...

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Detalles Bibliográficos
Autores principales: Dawood, Amal F., Al Humayed, Suliman, Momenah, Maha A., El-Sherbiny, Mohamed, Ashour, Hend, Kamar, Samaa S., ShamsEldeen, Asmaa M., Haidara, Mohamed A., Al-Ani, Bahjat, Ebrahim, Hasnaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322790/
https://www.ncbi.nlm.nih.gov/pubmed/35885665
http://dx.doi.org/10.3390/diagnostics12071762