Cargando…
Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis
Radiation exposure early in life is associated with greater incidences of malignancy. Our goal was to quantify radiation exposure in shunt-treated hydrocephalus patients and study changes in the diagnostic modalities used. A single-center, retrospective analysis was performed, and 41 children treate...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322797/ https://www.ncbi.nlm.nih.gov/pubmed/35884046 http://dx.doi.org/10.3390/children9071062 |
_version_ | 1784756392927690752 |
---|---|
author | Schabl, Lukas Küppers, Julia Jhala, Tobias Winicker, Hermann Esslinger, Peter Lehner, Markus |
author_facet | Schabl, Lukas Küppers, Julia Jhala, Tobias Winicker, Hermann Esslinger, Peter Lehner, Markus |
author_sort | Schabl, Lukas |
collection | PubMed |
description | Radiation exposure early in life is associated with greater incidences of malignancy. Our goal was to quantify radiation exposure in shunt-treated hydrocephalus patients and study changes in the diagnostic modalities used. A single-center, retrospective analysis was performed, and 41 children treated for hydrocephalus using an adjustable ventriculoperitoneal shunt were identified. Diagnostics associated with hydrocephalus and other comorbidities were analyzed and radiation exposure was calculated. During 330.09 total shunt years, patients were exposed to a mean hydrocephalus-associated radiation dose of 3.93 mSv (range: 0–24.38 mSv), which amounted to a mean rate of 0.49 mSv per shunt year, respectively. Radiation exposure was greatest after shunt insertion in the first year of life. A continuous change from CT scans to MRIs could be seen over the study period, such that patients who underwent shunt insertion after 2017 were not exposed to additional hydrocephalus-associated radiation during their first year of life. Nevertheless, our patients, and a few individuals especially, seemed to be at higher risk for radiation sequelae. Our results suggest that CT scans should be substituted with MRIs, which decrease overall radiation exposure and can lead to zero additional radiation exposure during the first year of life after shunt insertion. |
format | Online Article Text |
id | pubmed-9322797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93227972022-07-27 Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis Schabl, Lukas Küppers, Julia Jhala, Tobias Winicker, Hermann Esslinger, Peter Lehner, Markus Children (Basel) Article Radiation exposure early in life is associated with greater incidences of malignancy. Our goal was to quantify radiation exposure in shunt-treated hydrocephalus patients and study changes in the diagnostic modalities used. A single-center, retrospective analysis was performed, and 41 children treated for hydrocephalus using an adjustable ventriculoperitoneal shunt were identified. Diagnostics associated with hydrocephalus and other comorbidities were analyzed and radiation exposure was calculated. During 330.09 total shunt years, patients were exposed to a mean hydrocephalus-associated radiation dose of 3.93 mSv (range: 0–24.38 mSv), which amounted to a mean rate of 0.49 mSv per shunt year, respectively. Radiation exposure was greatest after shunt insertion in the first year of life. A continuous change from CT scans to MRIs could be seen over the study period, such that patients who underwent shunt insertion after 2017 were not exposed to additional hydrocephalus-associated radiation during their first year of life. Nevertheless, our patients, and a few individuals especially, seemed to be at higher risk for radiation sequelae. Our results suggest that CT scans should be substituted with MRIs, which decrease overall radiation exposure and can lead to zero additional radiation exposure during the first year of life after shunt insertion. MDPI 2022-07-16 /pmc/articles/PMC9322797/ /pubmed/35884046 http://dx.doi.org/10.3390/children9071062 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schabl, Lukas Küppers, Julia Jhala, Tobias Winicker, Hermann Esslinger, Peter Lehner, Markus Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title | Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title_full | Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title_fullStr | Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title_full_unstemmed | Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title_short | Global Irradiation in Children Treated for Hydrocephalus and Its Change over Time—A Single Institutional Analysis |
title_sort | global irradiation in children treated for hydrocephalus and its change over time—a single institutional analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322797/ https://www.ncbi.nlm.nih.gov/pubmed/35884046 http://dx.doi.org/10.3390/children9071062 |
work_keys_str_mv | AT schabllukas globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis AT kuppersjulia globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis AT jhalatobias globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis AT winickerhermann globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis AT esslingerpeter globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis AT lehnermarkus globalirradiationinchildrentreatedforhydrocephalusanditschangeovertimeasingleinstitutionalanalysis |