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Retinal Delivery of the Protein Kinase C-β Inhibitor Ruboxistaurin Using Non-Invasive Nanoparticles of Polyamidoamine Dendrimers

Ruboxistaurin (RBX) is an anti-vascular endothelial growth factor (anti-VEGF) agent that is used in the treatment of diabetic retinopathy and is mainly given intravitreally. To provide a safe and effective method for RBX administration, this study was designed to develop RBX nanoparticles using poly...

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Detalles Bibliográficos
Autores principales: Alshammari, Rehab A., Aleanizy, Fadilah S., Aldarwesh, Amal, Alqahtani, Fulwah Y., Mahdi, Wael A., Alquadeib, Bushra, Alqahtani, Qamraa H., Haq, Nazrul, Shakeel, Faiyaz, Abdelhady, Hosam G., Alsarra, Ibrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322846/
https://www.ncbi.nlm.nih.gov/pubmed/35890338
http://dx.doi.org/10.3390/pharmaceutics14071444