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Identification of COVID-19-Associated DNA Methylation Variations by Integrating Methylation Array and scRNA-Seq Data at Cell-Type Resolution
Single-cell transcriptome studies have revealed immune dysfunction in COVID-19 patients, including lymphopenia, T cell exhaustion, and increased levels of pro-inflammatory cytokines, while DNA methylation plays an important role in the regulation of immune response and inflammatory response. The spe...
Autores principales: | Wang, Guoliang, Xiong, Zhuang, Yang, Fei, Zheng, Xinchang, Zong, Wenting, Li, Rujiao, Bao, Yiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322889/ https://www.ncbi.nlm.nih.gov/pubmed/35885892 http://dx.doi.org/10.3390/genes13071109 |
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