Cargando…

Reduction of LPAR1 Expression in Neuroblastoma Promotes Tumor Cell Migration

SIMPLE SUMMARY: The tumor metastasis in the bone marrow or other organs in high-risk neuroblastoma patients is a serious problem to tackle and strongly impairs the survival of patients. Novel and effective targets for the treatment of neuroblastoma, especially tumor metastasis, need to be explored....

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiangjun, Pei, Mengmiao, Yu, Yongbo, Wang, Xiaolin, Gui, Jingang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322936/ https://www.ncbi.nlm.nih.gov/pubmed/35884407 http://dx.doi.org/10.3390/cancers14143346

Ejemplares similares

Interleukin-15 enhanced the survival of human γδT cells by regulating the expression of Mcl-1 in neuroblastoma
por: Wang, Hui, et al.
Publicado: (2022)

Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma
por: Wei, Jun S., et al.
Publicado: (2013)

Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes
por: He, Yi, et al.
Publicado: (2022)

In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity
por: Kuriyama, Sei, et al.
Publicado: (2014)

microRNA-329 reduces bone cancer pain through the LPAR1-dependent LPAR1/ERK signal transduction pathway in mice
por: Wu, Xian-Ping, et al.
Publicado: (2019)

Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses
por: Liu, Xiangjun, et al.
Publicado: (2023)

The Roles of Lpar1 in Central Nervous System Disorders and Diseases
por: Xiao, Dongqiong, et al.
Publicado: (2021)

Inhibition of LPA-LPAR1 and VEGF-VEGFR2 Signaling in IPF Treatment
por: Luo, Ya-Li, et al.
Publicado: (2023)

Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells
por: Hwang, Sung-Hee, et al.
Publicado: (2022)

Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells
por: Brusevold, Ingvild J, et al.
Publicado: (2014)

Designing Dual Inhibitors of Autotaxin-LPAR GPCR Axis
por: Banerjee, Souvik, et al.
Publicado: (2022)

An LPAR(5)-antagonist that reduces nociception and increases pruriception
por: Langedijk, Jacqueline, et al.
Publicado: (2022)

Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line
por: Rivera, Richard, et al.
Publicado: (2021)

Circular RNA LPAR3 sponges microRNA‐198 to facilitate esophageal cancer migration, invasion, and metastasis
por: Shi, Yijun, et al.
Publicado: (2020)

LPAR5 promotes thyroid carcinoma cell proliferation and migration by activating class IA PI3K catalytic subunit p110β
por: Zhao, Wei‐Jun, et al.
Publicado: (2021)

Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells
por: Zuckerman, Valentina, et al.
Publicado: (2015)

Long noncoding RNA ZFAS1 promotes tumorigenesis and metastasis in nasopharyngeal carcinoma by sponging miR‐892b to up‐regulate LPAR1 expression
por: Peng, Jiaojiao, et al.
Publicado: (2019)

LPAR1, Correlated With Immune Infiltrates, Is a Potential Prognostic Biomarker in Prostate Cancer
por: Shi, Jingqi, et al.
Publicado: (2020)

γδTFH cells promote B cell maturation and antibody production in neuroblastoma
por: Mou, Wenjun, et al.
Publicado: (2017)

Nectin2 influences cell apoptosis by regulating ANXA2 expression in neuroblastoma: Nectin2 influences SH-SY5Y cell migration and apoptosis
por: Zhang, Shihan, et al.
Publicado: (2023)

Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain
por: Rivera, Richard R., et al.
Publicado: (2020)

Lysophosphatidic acid mediates the pathogenesis of psoriasis by activating keratinocytes through LPAR5
por: Lei, Li, et al.
Publicado: (2021)

Lysophosphatidic Acid Receptor 6 (LPAR6) Is a Potential Biomarker Associated with Lung Adenocarcinoma
por: He, Jian, et al.
Publicado: (2021)

N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis
por: Juin, Amelie, et al.
Publicado: (2019)

Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti–PD-1 resistance in non–small cell lung cancer
por: Konen, Jessica M., et al.
Publicado: (2023)

AP003352.1/miR-141-3p axis enhances the proliferation of osteosarcoma by LPAR3
por: Yu, Hongde, et al.
Publicado: (2023)

LSD1 controls metastasis of androgen-independent prostate cancer cells through PXN and LPAR6
por: Ketscher, A, et al.
Publicado: (2014)

Lpar2b Controls Lateral Line Tissue Size by Regulating Yap1 Activity in Zebrafish
por: Wang, Xueqian, et al.
Publicado: (2018)

Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis
por: Takagi, Satoshi, et al.
Publicado: (2021)

Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex
por: Ghezzi, Filippo, et al.
Publicado: (2021)

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration
por: Villanueva, Andrea A., et al.
Publicado: (2016)

Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer
por: Ara, Hosne, et al.
Publicado: (2022)

Potential role of LPAR5 gene in prognosis and immunity of thyroid papillary carcinoma and pan-cancer
por: Zhang, Ben, et al.
Publicado: (2023)

Exosomal circLPAR1 Promoted Osteogenic Differentiation of Homotypic Dental Pulp Stem Cells by Competitively Binding to hsa-miR-31
por: Xie, Liangkun, et al.
Publicado: (2020)

TNRC6C-AS1 Promotes Thyroid Cancer Progression by Upregulating LPAR5 via miR-513c-5p
por: Tong, Chuanming, et al.
Publicado: (2021)

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance
por: Liu, Jianglan, et al.
Publicado: (2021)

Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
por: Yang, Shuping, et al.
Publicado: (2015)

miR-373 promotes neuroblastoma cell proliferation, migration, and invasion by targeting SRCIN1
por: Yuan, Xiu-Li, et al.
Publicado: (2019)

HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells
por: Kim, Nam-Ho, et al.
Publicado: (2019)

A Novel Prognostic Biomarker LPAR6 in Hepatocellular Carcinoma via Associating with Immune Infiltrates
por: He, Jian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ut11l4htjvlv0g2mroc6vjobll