Computational Methods in Cooperation with Experimental Approaches to Design Protein Tyrosine Phosphatase 1B Inhibitors in Type 2 Diabetes Drug Design: A Review of the Achievements of This Century

Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates phosphotyrosine residues and is an important regulator of several signaling pathways, such as insulin, leptin, and the ErbB signaling network, among others. Therefore, this enzyme is considered an attractive target to design new drugs against...

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Detalles Bibliográficos
Autores principales: Campos-Almazán, Mara Ibeth, Hernández-Campos, Alicia, Castillo, Rafael, Sierra-Campos, Erick, Valdez-Solana, Mónica, Avitia-Domínguez, Claudia, Téllez-Valencia, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322956/
https://www.ncbi.nlm.nih.gov/pubmed/35890163
http://dx.doi.org/10.3390/ph15070866

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